产品货号：
Z11288
中文名称：
APC6/CDC16抗体
英文名称：
Anti-APC6/CDC16 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-APC6/CDC16 Antibody |
| 指标别名 | ANAPC6;APC6;CDC16;CDC16 homolog;CDC16/APC6;CDC16Hs;Cyclosome subunit 6 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | CDC16 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | APC6 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human APC6.The immunogen is located within the first 50 amino acids of APC6. |
| 计算分子量 | 72kDa |
| 成分 | APC6 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | APC6 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis.APC6 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C),a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.APC/C is responsible for degrading anaphase inhibitors,mitotic cyclins,and spindle-associated proteins ensuring that events of mitosis take place in proper sequence.The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines,suggesting that they perform their functions as part of a complex.While little is known of APC6,it has been shown to interact with and is stabilized by CDC26 through an intermolecular TPR mimic composed of one helix from each protein. |
| Uniprot ID | Q13042 |
| 基因名全称 | Cell division cycle 16 homolog (S.cerevisiae) |
| 蛋白名全称 | Cell division cycle 16 homolog (S.cerevisiae) |
| 推荐稀释比 | APC6 antibody can be used for detection of APC6 by Western blot at 1 ～ 2μg/mL.Antibody can also be used for immunohistochemistry starting at 5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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